Ontology highlight
ABSTRACT:
SUBMITTER: Yoon K
PROVIDER: S-EPMC6693666 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Yoon Kyungho K Lee Wonhye W Chen Emily E Lee Ji Eun JE Croce Phillip P Cammalleri Amanda A Foley Lori L Tsao Allison L AL Yoo Seung-Schik SS
Ultrasound in medicine & biology 20190617 9
Transcranial application of focused ultrasound (FUS) combined with vascular introduction of microbubble contrast agents (MBs) has emerged as a non-invasive technique that can temporarily create a localized opening in the blood-brain barrier (BBB). Under image-guidance, we administered FUS to sheep brain after intravenous injection of microbubbles. BBB opening was confirmed by performing dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to detect the extravasated gadolinium-based mag ...[more]