Ontology highlight
ABSTRACT:
SUBMITTER: Romine ML
PROVIDER: S-EPMC6694118 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Romine Matthew L ML Li Mo M Liu Kevin Jiayang KJ Patel Sapna K SK Nelson Julie G JG Shen Ping P Cai Haini N HN
Scientific reports 20190814 1
Cell density regulates many aspects of cell properties and behaviors including metabolism, growth, cytoskeletal structure and locomotion. Importantly, the responses by cultured cells to density signals also uncover key mechanisms that govern animal development and diseases in vivo. Here we characterized a density-responsive reporter system in transgenic Drosophila S2 cells. We show that the reporter genes are strongly induced in a cell density-dependent and reporter-independent fashion. The rapi ...[more]