Ontology highlight
ABSTRACT:
SUBMITTER: Kunz TC
PROVIDER: S-EPMC6695470 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Kunz Tobias C TC Götz Ralph R Sauer Markus M Rudel Thomas T
Frontiers in cellular and infection microbiology 20190809
Expansion microscopy (ExM) is a novel tool to improve the resolution of fluorescence-based microscopy that has not yet been used to visualize intracellular pathogens. Here we show the expansion of the intracellular pathogen <i>Chlamydia trachomatis</i>, enabling to differentiate its two distinct forms, catabolic active reticulate bodies (RB) and infectious elementary bodies (EB), on a conventional confocal microscope. We show that ExM enables the possibility to precisely locate chlamydial effect ...[more]