Ontology highlight
ABSTRACT:
SUBMITTER: Luo Y
PROVIDER: S-EPMC6696325 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20190806 15
Four new lignan glycosides; urenalignosides A-D (<b>1</b>-<b>4</b>), along with 12 known ones (<b>5</b>-<b>16</b>) were isolated from <i>Urena lobata</i>. Their structures were determined on the basis of extensive spectroscopic and spectrometric data (1D and 2D NMR; IR; CD; and HRESIMS). Compounds <b>2</b>-<b>4</b>; <b>6</b>; <b>7</b>; <b>10</b>; and <b>11</b> showed inhibition of nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophage cells with IC<sub>50</sub> values in the ...[more]