Ontology highlight
ABSTRACT:
SUBMITTER: Frank I
PROVIDER: S-EPMC6700126 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Frank Ines I Acharya Arpan A Routhu Nanda K NK Aravantinou Meropi M Harper Justin L JL Maldonado Stephanie S Sole Cigoli Maria M Semova Stanka S Mazel Svetlana S Paiardini Mirko M Derby Nina N Byrareddy Siddappa N SN Martinelli Elena E
Scientific reports 20190819 1
The establishment of latent infection and poorly characterized viral reservoirs in tissues represent major obstacles to a definitive cure for HIV. Non-human primate (NHP) models of HIV infection are critical to elucidate pathogenic processes and an essential tool to test novel therapeutic strategies. Thus, the availability of novel assays to measure residual viral replication and reservoirs in NHP models may increase their utility in the search for an HIV cure. We developed a tat/rev induced lim ...[more]