Dataset Information

Effect of computerised cognitive training on cognitive outcomes in mild cognitive impairment: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To determine the effect of computerised cognitive training (CCT) on improving cognitive function for older adults with mild cognitive impairment (MCI).

Design

Systematic review and meta-analysis.

Data sources

PubMed, Embase, Web of Science and the Cochrane Library were searched through January 2018.

Eligibility criteria

Randomised controlled trials comparing CCT with control conditions in those with MCI aged 55+ were included.

Data extraction and synthesis

Two independent reviewers extracted data and assessed the risk of bias. Effect sizes (Hedges' g and 95% CIs) were calculated and random-effects meta-analyses were performed where three or more studies investigated a comparable intervention and outcome. Heterogeneity was quantified using the I² statistic.

Results

18 studies met the inclusion criteria and were included in the analyses, involving 690 participants. Meta-analysis revealed small to moderate positive treatment effects compared with control interventions in four domains as follows: global cognitive function (g=0.23, 95%?CI 0.03 to 0.44), memory (g=0.30, 95%?CI 0.11 to 0.50), working memory (g=0.39, 95%?CI 0.12 to 0.66) and executive function (g=0.20, 95%?CI -0.03 to 0.43). Statistical significance was reached in all domains apart from executive function.

Conclusions

This meta-analysis provides evidence that CCT improves cognitive function in older people with MCI. However, the long-term transfer of these improvements and the potential to reduce dementia prevalence remains unknown. Various methodological issues such as heterogeneity in outcome measures, interventions and MCI symptoms and lack of intention-to-treat analyses limit the quality of the literature and represent areas for future research.

SUBMITTER: Zhang H

PROVIDER: S-EPMC6701629 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Effect of computerised cognitive training on cognitive outcomes in mild cognitive impairment: a systematic review and meta-analysis.

Zhang Haifeng H Huntley Jonathan J Bhome Rohan R Holmes Benjamin B Cahill Jack J Gould Rebecca L RL Wang Huali H Yu Xin X Howard Robert R

BMJ open 20190818 8

<h4>Objectives</h4>To determine the effect of computerised cognitive training (CCT) on improving cognitive function for older adults with mild cognitive impairment (MCI).<h4>Design</h4>Systematic review and meta-analysis.<h4>Data sources</h4>PubMed, Embase, Web of Science and the Cochrane Library were searched through January 2018.<h4>Eligibility criteria</h4>Randomised controlled trials comparing CCT with control conditions in those with MCI aged 55+ were included.<h4>Data extraction and synthe ...[more]

PMID: 31427316

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Project description:Due to the growing number of older adults with cognitive impairment, it is essential to delay the onset and progression of cognitive decline and promote a healthy lifestyle. The rapid growth of technology has considerably advanced the field of computerized cognitive interventions. Consequently, traditional cognitive interventions are being adapted and new multimedia systems are being developed to encourage health and independent living in old age. The primary objective of this review was to identify cognitive stimulation, training and rehabilitation programs aimed at older people with mild cognitive impairment (MCI) and dementia. PsycINFO, Medline, CINAHL, Web of Science, PubMed, and CORDIS databases were searched from January 2008 to August 2018. Two researchers reviewed the potential studies individually for eligibility. Studies of computerized cognitive interventions for people with dementia and cognitive impairment were included if they clearly described objectives, users and functioning. A systematic review of the studies was carried out, providing a qualitative synthesis of the features and study characteristics of each software. Nineteen studies met the inclusion criteria, and 11 different cognitive stimulation, training, and rehabilitation programs were identified. The studies found on cognitive intervention software indicate the existence of various technological programs for people with MCI and dementia. On the overall, the programs were aimed at people with different clinical conditions, able to create specific treatments and personalized training, optimized for portable devices, and user-friendly. However, the selected programs differ from each other in terms of objectives, usage mode and characteristics, even if they were used for the same purposes. Therefore, the information obtained in the review may be relevant to distinguish between programs and select the one that best suits each user. Thus, more information about the features and context of use is needed as well as more clinical studies to be able to compare among computerized cognitive programs.

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Dataset Information

Effect of computerised cognitive training on cognitive outcomes in mild cognitive impairment: a systematic review and meta-analysis.

Objectives

Design

Data sources

Eligibility criteria

Data extraction and synthesis

Results

Conclusions

Publications

Effect of computerised cognitive training on cognitive outcomes in mild cognitive impairment: a systematic review and meta-analysis.

Similar Datasets

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