Ontology highlight
ABSTRACT:
SUBMITTER: Tojima T
PROVIDER: S-EPMC6703704 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Tojima Takuro T Suda Yasuyuki Y Ishii Midori M Kurokawa Kazuo K Nakano Akihiko A
Journal of cell science 20190802 15
The <i>trans</i>-Golgi network (TGN) acts as a sorting hub for membrane traffic. It receives newly synthesized and recycled proteins, and sorts and delivers them to specific targets such as the plasma membrane, endosomes and lysosomes/vacuoles. Accumulating evidence suggests that the TGN is generated from the <i>trans</i>-most cisterna of the Golgi by maturation, but the detailed transition processes remain obscure. Here, we examine spatiotemporal assembly dynamics of various Golgi/TGN-resident ...[more]