Ontology highlight
ABSTRACT:
SUBMITTER: Bu Q
PROVIDER: S-EPMC6704174 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Bu Qian Q Bu Qian Q Long Hailei H Shao Xue X Gu Hui H Kong Jueying J Luo Li L Liu Bin B Guo Wei W Wang Hongbo H Tian Jingwei J Zhao Yinglan Y Cen Xiaobo X
Translational psychiatry 20190821 1
Circular RNA (circRNA), a novel type of endogenous non-coding RNA, plays natural miRNA sponge effect that represses the activities of corresponding miRNAs through binding with them, thus modulating transcriptional expression of genes. Recent studies indicate that circRNAs are significantly enriched in the brain and some of them are derived from synaptic protein-coding genes. In addition, miRNAs are involved in synaptic plasticity, memory formation, and cocaine addiction. However, the role of cir ...[more]