Dataset Information

Quality of life among Sudanese patients with multiple sclerosis in Khartoum state using (MSQoL-54) questionnaire.

ABSTRACT:

Objective

To assess the quality of life, physical and mental factors, determine association between age, education status, disease duration and MSQOL-54 physical and Mental Health Composite scores among Sudanese patients with multiple sclerosis. This cross-section study was conducted among 32 MS patients at the National center for Neurological Science, Khartoum from January 2017 to June 2018. Using Multiple sclerosis Quality of life (MSQoL-54) questionnaire.

Results

Thirty two MS patients were participated in this study, 30 (94%) were females and 2 (6%) were males, 25 (78.1%) were found in age group < 40 years overall score of MSQoL-54 was 66.4 ± 21.9, Physical Health Composite (PHC) was 71.6 ± 21.3 and Mental Health Composite (MHC) was 61.2 ± 22.4. This study indicated that, non-graduated, advanced age and longer disease duration was significantly associated with poor Physical Health Composite and Mental Health Composite.

SUBMITTER: Ibrahim EAAE

PROVIDER: S-EPMC6704515 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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Publications

Quality of life among Sudanese patients with multiple sclerosis in Khartoum state using (MSQoL-54) questionnaire.

Ibrahim Etedal Ahmed Abu Elbasher EAAE Gassoum Alsadig A IshagAgib Israa El Imam IEI

BMC research notes 20190822 1

<h4>Objective</h4>To assess the quality of life, physical and mental factors, determine association between age, education status, disease duration and MSQOL-54 physical and Mental Health Composite scores among Sudanese patients with multiple sclerosis. This cross-section study was conducted among 32 MS patients at the National center for Neurological Science, Khartoum from January 2017 to June 2018. Using Multiple sclerosis Quality of life (MSQoL-54) questionnaire.<h4>Results</h4>Thirty two MS ...[more]

PMID: 31439008

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Project description:BackgroundChemotherapy-related toxicity affects the quality of life (QOL) of patients with cancer. Measuring the QOL in breast cancer (BC) patients has been the focus of clinical practices and research in recent decades. This study aimed to assess the impact of BC medications on QOL of Sudanese patients with BC.MethodsA cross-sectional study was conducted in Khartoum Oncology Hospital, Sudan, from November 2020 to March 2021. All patients diagnosed with BC were included in the study. QOL was assessed using the European Organization for Research and Treatment of Cancer quality of life (EORTC QLQ-C-30) and breast cancer supplementary module (QLQ-BR23). ANOVA, independent t-test and logistic regression analysis were used to assess the association between variables.ResultsTwo hundred patients were enrolled in the study, with a mean age of 50 ± 11.7 years. 52.5% of the patients were on a conventional therapy whereas 40.5% and 7% received hormonal and HER2-targeted therapies, respectively. In QLQ-C30 scale, the global health-QOL status score was (53.2 ± 1.9), with 54.0% of patients having poor global health-QOL status. In the functional scale, the cognitive functioning was the highest score (80.7 ± 1.8). In QLQ-C30 symptom scale, the most distressing issue was financial difficulties (63.7 ± 2.9). In QLQ-BR23 scale, body image scored the worse functioning (47.7 ± 2.7), with 54.5% of patients having poor QOL. In QLQ-BR23 symptoms scale, "being upset by hair loss" was the highest disturbing symptom (62.1 ± 3.3), with 68.6% of patients having poor QOL. Global health status (P = 0.000), social (P = 0.000), emotional (P = 0.002) and role functioning (P = 0.000) were significantly higher in patients taking HER2-targeted or hormonal therapy compared to conventional therapy. The level of symptomatology was significantly low in patients taking HER2-targeted therapy or hormonal therapy (P = 0.000) than those on conventional therapy. Hormonal (OR = 3.7, p = 0.01) and HER2-targeted therapies (OR = 10.2, p = 0.04 ) were positive predictors of QOL.ConclusionBC survivors in Sudan had a low QOL/global health status. Hormonal and HER2-targeted therapies were predictors of good QOL.

Dataset Information

Quality of life among Sudanese patients with multiple sclerosis in Khartoum state using (MSQoL-54) questionnaire.

Objective

Results

Publications

Quality of life among Sudanese patients with multiple sclerosis in Khartoum state using (MSQoL-54) questionnaire.

Similar Datasets

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