Ontology highlight
ABSTRACT:
SUBMITTER: Rasmark Roepke E
PROVIDER: S-EPMC6707182 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Scientific reports 20190823 1
Low-molecular-weight heparin (LMWH) is widely used to treat recurrent pregnancy loss (RPL) because of its anti-coagulant effects. Although in vitro studies have suggested additional immunological effects, these are debated. We therefore investigated whether LMWH could modulate immune responses in vivo during pregnancy of women with unexplained RPL. A Swedish open multi-centre randomised controlled trial included 45 women treated with tinzaparin and 42 untreated women. Longitudinally collected pl ...[more]