Regional changes in the elastic properties of myopic Guinea pig sclera.
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ABSTRACT:
SUBMITTER: Hoang QV
PROVIDER: S-EPMC6712578 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Regional changes in the elastic properties of myopic Guinea pig sclera.
Hoang Quan V QV Rohrbach Daniel D McFadden Sally A SA Mamou Jonathan J
Experimental eye research 20190719
Biomechanical changes in the sclera likely underlie the excessive eye elongation of axial myopia. We studied the biomechanical characteristics of myopic sclera at the microscopic level using scanning acoustic microscopy (SAM) with 7-μm in-plane resolution. Guinea pigs underwent form-deprivation (FD) in one eye from 4 to 12 days of age to induce myopia, and 12-μm-thick scleral cryosections were scanned using a custom-made SAM. Two-dimensional maps of the bulk modulus (K) and mass density (ρ) were ...[more]
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