Ontology highlight
ABSTRACT:
SUBMITTER: Puthran D
PROVIDER: S-EPMC6717141 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Puthran Divyaraj D Poojary Boja B Purushotham Nikil N Harikrishna Nandam N Nayak Soukhyarani Gopal SG Kamat Vinuta V
Heliyon 20190826 8
2-Amino-5-(3-fluoro-4-methoxyphenyl)thiophene-3-carbonitrile have been synthesized from 1-(3-fluoro-4-methoxyphenyl)ethanone, malononitrile, a mild base and sulfur powder using Gewald synthesis technique and the intermediate was treated with 1,3-disubstituted pyrazole-4-carboxaldehyde to obtain the novel Schiff bases. 1,3-disubstituted pyrazole-4-carboxaldehyde derivatives have been synthesized by Vilsmeier-Haack reaction in the course of a multi-step reaction. The structure of novel compounds w ...[more]