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Clinical neuroprosthetics: Today and tomorrow.


ABSTRACT: Implantable neurostimulation devices provide a direct therapeutic link to the nervous system and can be considered brain-computer interfaces (BCI). Under this definition, BCI are not simply science fiction, they are part of existing neurosurgical practice. Clinical BCI are standard of care for historically difficult to treat neurological disorders. These systems target the central and peripheral nervous system and include Vagus Nerve Stimulation, Responsive Neurostimulation, and Deep Brain Stimulation. Recent advances in clinical BCI have focused on creating "closed-loop" systems. These systems rely on biomarker feedback and promise individualized therapy with optimal stimulation delivery and minimal side effects. Success of clinical BCI has paralleled research efforts to create BCI that restore upper extremity motor and sensory function to patients. Efforts to develop closed loop motor/sensory BCI is linked to the successes of today's clinical BCI.

SUBMITTER: Lee MB 

PROVIDER: S-EPMC6717542 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Clinical neuroprosthetics: Today and tomorrow.

Lee Morgan B MB   Kramer Daniel R DR   Peng Terrance T   Barbaro Michael F MF   Liu Charles Y CY   Kellis Spencer S   Lee Brian B  

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20190730


Implantable neurostimulation devices provide a direct therapeutic link to the nervous system and can be considered brain-computer interfaces (BCI). Under this definition, BCI are not simply science fiction, they are part of existing neurosurgical practice. Clinical BCI are standard of care for historically difficult to treat neurological disorders. These systems target the central and peripheral nervous system and include Vagus Nerve Stimulation, Responsive Neurostimulation, and Deep Brain Stimu  ...[more]

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