Ontology highlight
ABSTRACT:
SUBMITTER: Kamal M
PROVIDER: S-EPMC6718421 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Nature communications 20190902 1
The nematode Caenorhabditis elegans is a bacterivore filter feeder. Through the contraction of the worm's pharynx, a bacterial suspension is sucked into the pharynx's lumen. Excess liquid is then shunted out of the buccal cavity through ancillary channels made by surrounding marginal cells. We find that many worm-bioactive small molecules (a.k.a. wactives) accumulate inside of the marginal cells as crystals or globular spheres. Through screens for mutants that resist the lethality associated wit ...[more]