Ontology highlight
ABSTRACT:
SUBMITTER: Dumaz N
PROVIDER: S-EPMC6721527 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Dumaz Nicolas N Jouenne Fanélie F Delyon Julie J Mourah Samia S Bensussan Armand A Lebbé Céleste C
Cancers 20190808 8
Primary mucosal melanomas represent a minority of melanomas, but have a significantly worse prognosis than cutaneous melanomas. A better characterization of the molecular pathogenesis of this melanoma subtype could help us understand the risk factors associated with the development of mucosal melanomas and highlight therapeutic targets. Because the Mitogen-Activated Protein Kinase (MAPK) pathway plays such a significant role in melanoma development, we explore v-raf murine sarcoma viral oncogene ...[more]