Ontology highlight
ABSTRACT:
SUBMITTER: Zhang P
PROVIDER: S-EPMC6721685 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Zhang Pengpeng P Chao Zhe Z Zhang Rui R Ding Ruoqi R Wang Yaling Y Wu Wei W Han Qiu Q Li Cencen C Xu Haixia H Wang Lei L Xu Yongjie Y
Cells 20190813 8
Circular RNA (circRNA) is a novel class of non-coding RNA generated by pre-mRNA back splicing, which is characterized by a closed-loop structure. Although circRNAs were firstly reported decades ago, their regulatory roles have not been discovered until recently. In this review, we discussed the putative biogenesis pathways and regulatory functions of circRNAs. Recent studies showed that circRNAs are abundant in skeletal muscle tissue, and their expression levels are regulated during muscle devel ...[more]