Ontology highlight
ABSTRACT:
SUBMITTER: Akoury E
PROVIDER: S-EPMC6722631 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Journal of clinical medicine 20190814 8
Zoledronate (Zol) is an anti-resorptive/tumoral agent used for the treatment of many cancers including spinal bone metastasis. High systemic administration of a single dose is now the standard clinical care, yet it has been associated with several side effects. Here, we aimed to evaluate the effects of lower doses Zol on lung cancer and lung cancer-induced bone metastasis cells over a longer time period. Human lung cancer (HCC827) and three bone metastases secondary to lung cancer (BML1, BML3 an ...[more]