Ontology highlight
ABSTRACT:
SUBMITTER: Chang YT
PROVIDER: S-EPMC6722774 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Chang Yun-Te YT Kung Ming-Hsiang MH Hsu Thung-Hsien TH Hung Wan-Ting WT Chen Yao-Shen YS Yen Li-Chen LC Chang Tsung-Hsien TH
Viruses 20190819 8
The picornavirus Aichi virus (AiV) is a non-enveloped RNA virus that causes acute gastroenteritis symptoms, such as diarrhea, abdominal pain, nausea, vomiting, and fever. Antiviral host defense involves the fast response of type I interferon (IFN) and the secretion of inflammatory cytokines against pathogens. However, the intestinal inflammatory and antiviral response to AiV infection is poorly understood. This study evaluated the antiviral activity of intestinal epithelial cells (IECs), which f ...[more]