Ontology highlight
ABSTRACT:
SUBMITTER: Konig NF
PROVIDER: S-EPMC6726599 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
König Niklas Felix NF Al Ouahabi Abdelaziz A Oswald Laurence L Szweda Roza R Charles Laurence L Lutz Jean-François JF
Nature communications 20190904 1
Light-induced alteration of macromolecular information plays a central role in biology and is known to influence health, aging and Darwinian evolution. Here, we report that light can also trigger sequence variations in abiotic information-containing polymers. Sequence-coded poly(phosphodiester)s were synthesized using four phosphoramidite monomers containing either photo-sensitive or photo-inert substituents. These monomers allow different sequence manipulations. For instance, using two light-cl ...[more]