Ontology highlight
ABSTRACT:
SUBMITTER: Nickaeen M
PROVIDER: S-EPMC6727779 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Nickaeen Masoud M Berro Julien J Pollard Thomas D TD Slepchenko Boris M BM
Molecular biology of the cell 20190626 16
We formulated a spatially resolved model to estimate forces exerted by a polymerizing actin meshwork on an invagination of the plasma membrane during endocytosis in yeast cells. The model, which approximates the actin meshwork as a visco-active gel exerting forces on a rigid spherocylinder representing the endocytic invagination, is tightly constrained by experimental data. Simulations of the model produce forces that can overcome resistance of turgor pressure in yeast cells. Strong forces emerg ...[more]