Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC6731132 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Wang Yucai Y Maurer Matthew J MJ Larson Melissa C MC Allmer Cristine C Feldman Andrew L AL Bennani N Nora NN Thompson Carrie A CA Porrata Luis F LF Habermann Thomas M TM Witzig Thomas E TE Ansell Stephen M SM Slager Susan L SL Nowakowski Grzegorz S GS Cerhan James R JR
British journal of haematology 20190528 6
The diabetes mellitus (DM) drug metformin targets mechanistic/mammalian target of rapamycin and inhibits lymphoma growth in vitro. We investigated whether metformin affected outcomes of newly diagnosed diffuse large B-cell (DLBCL, n = 869) and follicular lymphoma (FL, n = 895) patients enrolled in the Mayo component of the Molecular Epidemiology Resource cohort study between 2002 and 2015. Hazard ratios (HR) and 95% confidence intervals (CIs) adjusted for age, sex, body mass index, prognostic in ...[more]