Ontology highlight
ABSTRACT:
SUBMITTER: Conway GE
PROVIDER: S-EPMC6733837 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Conway Gillian E GE He Zhonglei Z Hutanu Ana Lacramioara AL Cribaro George Paul GP Manaloto Eline E Casey Alan A Traynor Damien D Milosavljevic Vladimir V Howe Orla O Barcia Carlos C Murray James T JT Cullen Patrick J PJ Curtin James F JF
Scientific reports 20190909 1
Room temperature Cold Atmospheric Plasma (CAP) has shown promising efficacy for the treatment of cancer but the exact mechanisms of action remain unclear. Both apoptosis and necrosis have been implicated as the mode of cell death in various cancer cells. We have previously demonstrated a caspase-independent mechanism of cell death in p53-mutated glioblastoma multiforme (GBM) cells exposed to plasma. The purpose of this study was to elucidate the molecular mechanisms involved in caspase-independe ...[more]