Ontology highlight
ABSTRACT:
SUBMITTER: Ohtsuka J
PROVIDER: S-EPMC6733870 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20190909 1
Ectopic protein with proper steric structure was efficiently loaded onto the envelope of the F gene-defective BC-PIV vector derived from human parainfluenza virus type 2 (hPIV2) by a reverse genetics method of recombinant virus production. Further, ectopic antigenic peptide was successfully loaded either outside, inside, or at both sides of the envelope of the vector. The BC-PIV vector harboring the Ebola virus GP gene was able to elicit neutralizing antibodies in mice. In addition, BC-PIV with ...[more]