The Tyrosine-Autokinase UbK Is Required for Proper Cell Growth and Cell Morphology of Streptococcus pneumoniae.
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ABSTRACT:
SUBMITTER: Pelletier A
PROVIDER: S-EPMC6733980 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
The Tyrosine-Autokinase UbK Is Required for Proper Cell Growth and Cell Morphology of <i>Streptococcus pneumoniae</i>.
Pelletier Anaïs A Freton Céline C Gallay Clément C Trouve Jennyfer J Cluzel Caroline C Franz-Wachtel Mirita M Macek Boris B Jault Jean-Michel JM Grangeasse Christophe C Guiral Sébastien S
Frontiers in microbiology 20190903
Protein phosphorylation is a key post-translational modification required for many cellular functions of the bacterial cell. Recently, we identified a new protein-kinase, named UbK, in <i>Bacillus subtilis</i> that belongs to a new family of protein-kinases widespread in bacteria. In this study, we analyze the function of UbK in <i>Streptococcus pneumoniae</i>. We show that UbK displays a tyrosine-kinase activity and autophosphorylates on a unique tyrosine <i>in vivo</i>. To get insights into it ...[more]
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2016-12-08 | GSE19791 | GEO
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