Ontology highlight
ABSTRACT:
SUBMITTER: Favoni V
PROVIDER: S-EPMC6734543 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Favoni Valentina V Giani Luca L Al-Hassany Linda L Asioli Gian Maria GM Butera Calogera C de Boer Irene I Guglielmetti Martina M Koniari Chrysoula C Mavridis Theodoros T Vaikjärv Marge M Verhagen Iris I Verzina Angela A Zick Bart B Martelletti Paolo P Sacco Simona S
The journal of headache and pain 20190312 1
Calcitonin gene-related peptide (CGRP) is a neuropeptide with a pivotal role in the pathophysiology of migraine. Blockade of CGRP is a new therapeutic target for patients with migraine. CGRP and its receptors are distributed not only in the central and peripheral nervous system but also in the cardiovascular system, both in blood vessels and in the heart. We reviewed the current evidence on the role of CGRP in the cardiovascular system in order to understand the possible short- and long-term eff ...[more]