Ontology highlight
ABSTRACT:
SUBMITTER: Smith R
PROVIDER: S-EPMC6736605 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Smith Rebecca R Devlin Kaylyn K Kilburn David D Gross Sean S Sudar Damir D Bucher Elmar E Nederlof Michel M Dane Mark M Gray Joe W JW Heiser Laura L Korkola James E JE
Journal of visualized experiments : JoVE 20190521 147
Understanding the impact of the microenvironment on the phenotype of cells is a difficult problem due to the complex mixture of both soluble growth factors and matrix-associated proteins in the microenvironment in vivo. Furthermore, readily available reagents for the modeling of microenvironments in vitro typically utilize complex mixtures of proteins that are incompletely defined and suffer from batch to batch variability. The microenvironment microarray (MEMA) platform allows for the assessmen ...[more]