Ontology highlight
ABSTRACT:
SUBMITTER: Rycaj K
PROVIDER: S-EPMC5491097 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Rycaj Kiera K Li Hangwen H Zhou Jianjun J Chen Xin X Tang Dean G DG
Seminars in cancer biology 20170411
Metastasis causes more than 90% of cancer-related deaths and most prostate cancer (PCa) patients also die from metastasis. The 'metastatic cascade' is a complex biological process that encompasses tumor cell dissociation (from the primary tumor), local invasion, intravasation, transport in circulation, extravasation, colonization, and overt growth in end organs. It has become clear that successful metastasis not only involves many tumor cell-intrinsic properties but also depends on productive in ...[more]