Ontology highlight
ABSTRACT:
SUBMITTER: Hou J
PROVIDER: S-EPMC6737273 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Science advances 20190710 7
Cerebral ischemia (CI) results from inadequate blood flow to the brain. The difficulty of delivering therapeutic molecules to lesions resulting from CI hinders the effective treatment of this disease. The inflammatory response following CI offers a unique opportunity for drug delivery to the ischemic brain and targeted cells because of the recruitment of leukocytes to the stroke core and penumbra. In the present study, neutrophils and monocytes were explored as cell carriers after selectively ca ...[more]