Ontology highlight
ABSTRACT:
SUBMITTER: Miller VM
PROVIDER: S-EPMC6738629 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Miller Virginia M VM Naftolin Fredrick F Asthana Sanjay S Black Dennis M DM Brinton Eliot A EA Budoff Matthew J MJ Cedars Marcelle I MI Dowling N Maritza NM Gleason Carey E CE Hodis Howard N HN Jayachandran Muthuvel M Kantarci Kejal K Lobo Rogerio A RA Manson JoAnn E JE Pal Lubna L Santoro Nanette F NF Taylor Hugh S HS Harman S Mitchell SM
Menopause (New York, N.Y.) 20190901 9
<h4>Objective</h4>The Kronos Early Estrogen Prevention Study (KEEPS) was designed to address gaps in understanding the effects of timely menopausal hormone treatments (HT) on cardiovascular health and other effects of menopause after the premature termination of the Women's Health Initiative.<h4>Method</h4>The KEEPS was a randomized, double-blinded, placebo-controlled trial to test the hypothesis that initiation of HT (oral conjugated equine estrogens [o-CEE] or transdermal 17β-estradiol [t-E2]) ...[more]