Ontology highlight
ABSTRACT:
SUBMITTER: Koppel N
PROVIDER: S-EPMC6740198 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Molecular biology of the cell 20190814 20
Key genes, such as <i>Agrin</i>, <i>Lrp4</i>, and <i>MuSK</i>, are required for the initial formation, subsequent maturation, and long-term stabilization of mammalian neuromuscular synapses. Additional molecules are thought to function selectively during the evolution and stabilization of these synapses, but these molecular players are largely unknown. Here, we used mass spectrometry to identify vezatin, a two-pass transmembrane protein, as an acetylcholine receptor (AChR)-associated protein, an ...[more]