Ontology highlight
ABSTRACT:
SUBMITTER: Gancheva S
PROVIDER: S-EPMC6744497 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Nature communications 20190913 1
The mechanisms underlying improved insulin sensitivity after surgically-induced weight loss are still unclear. We monitored skeletal muscle metabolism in obese individuals before and over 52 weeks after metabolic surgery. Initial weight loss occurs in parallel with a decrease in muscle oxidative capacity and respiratory control ratio. Persistent elevation of intramyocellular lipid intermediates, likely resulting from unrestrained adipose tissue lipolysis, accompanies the lack of rapid changes in ...[more]