Ontology highlight
ABSTRACT:
SUBMITTER: Ettrich TJ
PROVIDER: S-EPMC6744511 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Ettrich T J TJ Schwerdel D D Dolnik A A Beuter F F Blätte T J TJ Schmidt S A SA Stanescu-Siegmund N N Steinacker J J Marienfeld R R Kleger A A Bullinger L L Seufferlein T T Berger A W AW
Scientific reports 20190913 1
Diagnosis of Cholangiocarcinoma (CCA) is difficult, thus a noninvasive approach towards (i) assessing and (ii) monitoring the tumor-specific mutational profile is desirable to improve diagnosis and tailor treatment. Tumor tissue and corresponding ctDNA samples were collected from patients with CCA prior to and during chemotherapy and were subjected to deep sequencing of 15 genes frequently mutated in CCA. A set of ctDNA samples was also submitted for 710 gene oncopanel sequencing to identify pro ...[more]