Ontology highlight
ABSTRACT:
SUBMITTER: Rivas M
PROVIDER: S-EPMC6746434 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
AIChE journal. American Institute of Chemical Engineers 20180908 12
The successful engineering of biosynthetic pathways hinges on understanding the factors that influence acyl carrier protein (ACP) stability and function. The stability and structure of ACPs can be influenced by the presence of divalent cations, but how this relates to primary sequence remains poorly understood. As part of a course-based undergraduate research experience, we investigated the thermostability of type II polyketide synthase (PKS) ACPs. We observed an approximate 40 °C range in the t ...[more]