Ontology highlight
ABSTRACT:
SUBMITTER: Xu J
PROVIDER: S-EPMC6747175 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Xu Jian J Kato Tatsuya T Park Enoch Y EY
International journal of molecular sciences 20190829 17
Protein conjugations at post-translational levels are known to be essential to protein stability and function. Recently, it has been proven that the split protein CnaB2 (SpyTag/SpyCatcher, ST/SC) from <i>Streptococcus pyogenes</i> can induce covalent conjugation rapidly and efficiently under various conditions. The protein of interest fused with the split protein SC/ST could be assembled spontaneously. In light of this finding, we introduced the ST/SC protein coupling concept into the silkworm-b ...[more]