Ontology highlight
ABSTRACT:
SUBMITTER: Carrillo-Reid L
PROVIDER: S-EPMC6747687 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Carrillo-Reid Luis L Han Shuting S Yang Weijian W Akrouh Alejandro A Yuste Rafael R
Cell 20190627 2
Neurons in cortical circuits are often coactivated as ensembles, yet it is unclear whether ensembles play a functional role in behavior. Some ensemble neurons have pattern completion properties, triggering the entire ensemble when activated. Using two-photon holographic optogenetics in mouse primary visual cortex, we tested whether recalling ensembles by activating pattern completion neurons alters behavioral performance in a visual task. Disruption of behaviorally relevant ensembles by activati ...[more]