Ontology highlight
ABSTRACT:
SUBMITTER: Zhou B
PROVIDER: S-EPMC6750104 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Research (Washington, D.C.) 20180905
Two pairs of enantiomers, (-) and (+)-securidanes A (<b>1</b> and <b>2</b>) and B (<b>3</b> and <b>4</b>) featuring unprecedented triarylmethane (TAM) skeletons, were isolated from <i>Securidaca inappendiculata</i>. Their structures were established by spectroscopic data, X-ray crystallography, and CD analysis. A plausible biosynthetic pathway for <b>1</b>-<b>4</b> based on the co-isolated precursors was proposed. Bioinspired total synthesis of <b>1</b>-<b>4</b> was completed in high yield, whic ...[more]