Ontology highlight
ABSTRACT:
SUBMITTER: Foguet C
PROVIDER: S-EPMC6750616 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Foguet Carles C Jayaraman Anusha A Marin Silvia S Selivanov Vitaly A VA Moreno Pablo P Messeguer Ramon R de Atauri Pedro P Cascante Marta M
PLoS computational biology 20190906 9
Deciphering the mechanisms of regulation of metabolic networks subjected to perturbations, including disease states and drug-induced stress, relies on tracing metabolic fluxes. One of the most informative data to predict metabolic fluxes are 13C based metabolomics, which provide information about how carbons are redistributed along central carbon metabolism. Such data can be integrated using 13C Metabolic Flux Analysis (13C MFA) to provide quantitative metabolic maps of flux distributions. Howev ...[more]