Dataset Information
Hydrogen Sulfide Mediated Tandem Reaction of Selenenyl Sulfides and Its Application in Fluorescent Probe Development.
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ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC6756184 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Hydrogen Sulfide Mediated Tandem Reaction of Selenenyl Sulfides and Its Application in Fluorescent Probe Development.
Organic letters 20190906 18
A unique reaction between H<sub>2</sub>S and a selenenyl sulfide containing benzoate ester template was discovered. This reaction could be specifically triggered by H<sub>2</sub>S and lead to ester bond cleavage. The reaction was not affected by the presence of thiols such as glutathione and cysteine. With this reaction, a series of fluorescent probes were synthesized and evaluated. The probes exhibited high sensitivity/selectivity for H<sub>2</sub>S in both buffers and cells. ...[more]