Ontology highlight
ABSTRACT:
SUBMITTER: Economides MP
PROVIDER: S-EPMC6759709 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Economides Minas P MP Konopleva Marina M Pemmaraju Naveen N
Therapeutic advances in hematology 20190923
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive hematologic malignancy derived from precursors of dendritic cells and involves most frequently the skin, bone marrow and lymph nodes. Diagnosis depends upon identification of specific tumor markers including CD4, CD56 and CD123. Historically, the median survival has been less than 2 years in most reported series. While for many years, conventional chemotherapy followed by stem cell transplantation was the standard of ...[more]