Ontology highlight
ABSTRACT:
SUBMITTER: Faltracco M
PROVIDER: S-EPMC6760471 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20190910 18
We report the intramolecular Tsuji-Trost reaction of Ugi adducts to give spiro-diketopiperazines in high yield and with high enantioselectivity. This approach allows the catalytic asymmetric construction of a broad range of these medicinally important heterocycles under mild conditions, in two steps from cheap, commercially available starting materials. ...[more]