Ontology highlight
ABSTRACT:
SUBMITTER: Wang ZJ
PROVIDER: S-EPMC7091330 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Organic letters 20190807 16
A radical-mediated functionalization of allyl alcohol derived partners with a variety of alkyl 1,4-dihydropyridines via photoredox/nickel dual catalysis is described. This transformation transpires with high linear and <i>E</i>-selectivity, avoiding the requirement of harsh conditions (e.g., strong base, elevated temperature). Additionally, using aryl sulfinate salts as radical precursors, allyl sulfones can also be obtained. Kinetic isotope effect experiments implicated oxidative addition of th ...[more]