Ontology highlight
ABSTRACT:
SUBMITTER: He C
PROVIDER: S-EPMC6761745 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
ACS omega 20190909 13
A one-pot gold-catalyzed hydroalkoxylation/Povarov reaction cascade of alkynols with <i>N</i>-aryl imines or in situ generated iminium has been developed. The protocol provides a facile access to a series of fused tricyclic tetrahydroquinolines with a broad substrate scope using readily available materials under mild conditions. The unique mechanistic feature is the dual function of the gold catalyst, which first catalyzed the intramolecular hydroalkoxylation of alkynols, and upon the formation ...[more]