Ontology highlight
ABSTRACT:
SUBMITTER: Gittelman RM
PROVIDER: S-EPMC6764441 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Gittelman Rachel M RM Schraiber Joshua G JG Vernot Benjamin B Mikacenic Carmen C Wurfel Mark M MM Akey Joshua M JM
Current biology : CB 20161110 24
As modern humans dispersed from Africa throughout the world, they encountered and interbred with archaic hominins, including Neanderthals and Denisovans [1, 2]. Although genome-scale maps of introgressed sequences have been constructed [3-6], considerable gaps in knowledge remain about the functional, phenotypic, and evolutionary significance of archaic hominin DNA that persists in present-day individuals. Here, we describe a comprehensive set of analyses that identified 126 high-frequency archa ...[more]