Ontology highlight
ABSTRACT:
SUBMITTER: van Vliet S
PROVIDER: S-EPMC6764841 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
van Vliet Simon S Dal Co Alma A Winkler Annina R AR Spriewald Stefanie S Stecher Bärbel B Ackermann Martin M
Cell systems 20180411 4
Gene expression levels in clonal bacterial groups have been found to be spatially correlated. These correlations can partly be explained by the shared lineage history of nearby cells, although they could also arise from local cell-cell interactions. Here, we present a quantitative framework that allows us to disentangle the contributions of lineage history, long-range spatial gradients, and local cell-cell interactions to spatial correlations in gene expression. We study pathways involved in tox ...[more]