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The relationship of longitudinal cognitive change to self-reported IADL in a general population.


ABSTRACT: This study examined the relationship between cognitive change and instrumental activities of daily living (IADL) in a large, national, population-based sample. Cognitive change was assessed via verbal fluency, word list learning (WLL), and word list delayed recall (WLD). Incident cognitive impairment was defined by change in Six-Item Screener (SIS) status over a period of 10 years. Impaired IADL was defined as self-reported difficulty or needing assistance performing any IADL at Year 10. A one-word decrease in WLL over a 10-year span increased the odds of impaired IADL by 16% (95% CI 1.08-1.24) and incident cognitive impairment increased the odds of impaired IADL by 59% (95% CI 1.36-1.85) when adjusting for demographic factors, health-related behaviors, vascular risk factors and disease, and depressive symptoms. Cognitive change most strongly predicted impairment in managing finances (OR 2.47, 95% CI 2.04-3.00) and driving (OR 2.06, 95% CI 1.73-2.44).

SUBMITTER: Passler JS 

PROVIDER: S-EPMC6764909 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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The relationship of longitudinal cognitive change to self-reported IADL in a general population.

Passler Jesse S JS   Kennedy Richard E RE   Clay Olivio J OJ   Crowe Michael M   Howard Virginia J VJ   Cushman Mary M   Unverzagt Frederick W FW   Wadley Virginia G VG  

Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition 20190327 1


This study examined the relationship between cognitive change and instrumental activities of daily living (IADL) in a large, national, population-based sample. Cognitive change was assessed via verbal fluency, word list learning (WLL), and word list delayed recall (WLD). Incident cognitive impairment was defined by change in Six-Item Screener (SIS) status over a period of 10 years. Impaired IADL was defined as self-reported difficulty or needing assistance performing any IADL at Year 10. A one-w  ...[more]

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