The relationship of cognitive change over time to the self-reported Ascertain Dementia 8-item Questionnaire in a general population.

ABSTRACT:

Objective

The aim of the study was to examine the relationship between longitudinally assessed cognitive functioning and self-reported dementia status using the Ascertain Dementia 8-item questionnaire (AD8) in a national population-based sample.

Methods

The analysis included 14,453 participants from the REasons for Geographic and Racial Differences in Stroke study. A validated cutoff of ≥2 symptoms endorsed on the AD8 (administered 10 years after enrollment) represented positive AD8 status. Incident cognitive impairment was defined as change from intact to impaired status in the Six-Item Screener score, and cognitive decline was defined by trajectories of Letter "F" Fluency from the Montreal Cognitive Assessment, and Animal Fluency, Word List Learning, and Word List Delayed

SUBMITTER: Passler JS 

PROVIDER: S-EPMC7881974 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature