Ontology highlight
ABSTRACT:
SUBMITTER: Infante M
PROVIDER: S-EPMC6769474 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Infante Marco M Ricordi Camillo C Sanchez Janine J Clare-Salzler Michael J MJ Padilla Nathalia N Fuenmayor Virginia V Chavez Carmen C Alvarez Ana A Baidal David D Alejandro Rodolfo R Caprio Massimiliano M Fabbri Andrea A
Nutrients 20190911 9
Type 1 diabetes (T1D) is a chronic autoimmune disease leading to immune-mediated destruction of pancreatic beta cells, resulting in the need for insulin therapy. The incidence of T1D is increasing worldwide, thus prompting researchers to investigate novel immunomodulatory strategies to halt autoimmunity and modify disease progression. T1D is considered as a multifactorial disease, in which genetic predisposition and environmental factors interact to promote the triggering of autoimmune responses ...[more]