Ontology highlight
ABSTRACT:
SUBMITTER: Carbonell D
PROVIDER: S-EPMC6770229 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Carbonell Diego D Suárez-González Julia J Chicano María M Andrés-Zayas Cristina C Triviño Juan Carlos JC Rodríguez-Macías Gabriela G Bastos-Oreiro Mariana M Font Patricia P Ballesteros Mónica M Muñiz Paula P Balsalobre Pascual P Kwon Mi M Anguita Javier J Díez-Martín José Luis JL Buño Ismael I Martínez-Laperche Carolina C
Cancers 20190913 9
Molecular diagnosis of myeloid neoplasms (MN) is based on the detection of multiple genetic alterations using various techniques. Next-generation sequencing (NGS) has been proved as a useful method for analyzing many genes simultaneously. In this context, we analyzed diagnostic samples from 121 patients affected by MN and ten relapse samples from a subset of acute myeloid leukemia patients using two enrichment-capture NGS gene panels. Pathogenicity classification of variants was enhanced by the ...[more]