Ontology highlight
ABSTRACT:
SUBMITTER: Little MH
PROVIDER: S-EPMC6771389 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Little Melissa H MH Combes Alexander N AN
Genes & development 20191001 19-20
There are now many reports of human kidney organoids generated via the directed differentiation of human pluripotent stem cells (PSCs) based on an existing understanding of mammalian kidney organogenesis. Such kidney organoids potentially represent tractable tools for the study of normal human development and disease with improvements in scale, structure, and functional maturation potentially providing future options for renal regeneration. The utility of such organotypic models, however, will u ...[more]