Ontology highlight
ABSTRACT:
SUBMITTER: von Holst S
PROVIDER: S-EPMC6777498 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
von Holst Susanna S Jiao Xiang X Liu Wen W Kontham Vinaykumar V Thutkawkorapin Jessada J Ringdahl Jenny J Bryant Patrick P Lindblom Annika A
European journal of human genetics : EJHG 20190405 8
Colorectal cancer (CRC) is one of the major cancer types in the western world including Sweden. However, known genetic risk factors could only explain a limited part of heritability of the disease. Moreover, colon and rectal cancers are habitually discussed as one entity, colorectal cancer, although different carcinogenesis has been recognized. A genome-wide linkage scan in 32 colon- and 56 rectal cancer families from Sweden was performed based on 475 non-FAP/HNPCC patients genotyped using SNP a ...[more]